Effect ofHelicteres isora. Bark Extracts on Brain Antioxidant Status and Lipid Peroxidation in Streptozotocin Diabetic Rats

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Effect of Helicteres isora Bark Extracts on Brain Antioxidant Status and Lipid Peroxidation in Streptozotocin Diabetic Rats

The current study investigated the effect of the aqueous extract of Helicteres isora L (Sterculiaceae) bark on oxidative stress in the brains of rats during diabetes. The aqueous extract of H. isora bark was administered orally (100, 200mg=kg b.w.) and the effect of the extract on blood glucose, plasma insulin, and the levels of thiobarbituric acid reactive substances (TBARS), hydroperoxides, s...

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Effect of Helicteres isora Bark Extract on Protein Metabolism and Marker Enzymes in Streptozotocin-Induced Diabetic Rats

The present study investigated the possible protective effect of Helicteres isora (Sterculiaceae) bark extracts on certain biochemical markers in streptozotocin (STZ)-induced diabetes in rats. STZ treatment (60 mg/kg/i.p) caused a hyperglycemic state that led to various physiological and biochemical alterations. Blood levels of glucose, urea, uric acid and creatinine, plasma levels of albumin a...

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Effect of Helicteres isora Bark Extract on Protein Metabolism and Marker Enzymes in Streptozotocin-Induced Diabetic Rats

The present study investigated the possible protective effect of Helicteres isora (Sterculiaceae) bark extracts on certain biochemical markers in streptozotocin (STZ)-induced diabetes in rats. STZ treatment (60 mg/kg/i.p) caused a hyperglycemic state that led to various physiological and biochemical alterations. Blood levels of glucose, urea, uric acid and creatinine, plasma levels of albumin a...

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The effects of dietary caloric restriction on antioxidant status and lipid peroxidation in mild and severe streptozotocin-induced diabetic rats.

BACKGROUND Dietary caloric restriction (CR) without malnutrition is effective in the control of diabetes mellitus by stabilizing glucose homeostasis and enhancing glycemic control. Mild and severe streptozotocin-induced diabetic and non-diabetic rats were subjected to caloric restriction and ad libitum feeding to evaluate their effects on oxidative stress and lipid profile in the plasma of expe...

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Antioxidant status and lipid peroxidation in diabetic pregnancy.

Pregnancy in insulin-dependent diabetes mellitus is associated with a greater incidence of fetal abnormality. Animal studies suggest that increased free-radical production and antioxidant depletion may contribute to this risk. The aim of the present study was, therefore, to assess nutritional antioxidant status and lipid peroxidation in diabetic mothers in comparison with a control group. A 7 d...

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ژورنال

عنوان ژورنال: Pharmaceutical Biology

سال: 2007

ISSN: 1388-0209,1744-5116

DOI: 10.1080/13880200701585782